One thing I use now is pidgin-microblog, which is interesting also. Previously, the way to connect to twitter using pidgin, is to use a jabber account like google chat, then add twitter. But ever since, twitter, shut down the jabber service. SO it don't work anymore.
On the other hand, pidgin-microblog, works quite well.
It's still new, but still, it is interesting to see, how creative people be with pidgin